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Madelung deformity is a congenital skeletal condition primarily affecting the wrist, characterized by a disruption in the normal growth of the distal radius, resulting in an irregular alignment of the wrist bones. This deformity is most often observed in females and typically manifests during childhood or adolescence, becoming more pronounced with the growth and development of the skeletal system. Clinically, individuals with Madelung deformity may present with a variety of symptoms, including limitations in wrist mobility, pain, and cosmetic deformity associated with a distinctive palmar bowing of the distal radius and an ulnar deviation of the wrist. The exact cause of Madelung deformity has not been fully elucidated, but it is believed to be related to abnormal growth patterns, often linked to genetic factors. Some studies suggest that it may arise from a malformation in the growth of the radius, possibly due to an imbalance in the forces exerted by the surrounding soft tissue structures, such as the ligaments and tendons. This condition can also be associated with other syndromes; for example, it has been linked to Ehlers-Danlos syndrome and Madelung-like deformities, indicating a potential genetic predisposition that could influence its occurrence. The condition may also be exacerbated by hormonal influences, mechanical stresses during growth, or even injuries to the wrist area. Patients with Madelung deformity often report difficulties with activities requiring wrist function, including typing or participating in sports, with younger individuals particularly affected due to the social and physical implications of visible deformities. Diagnosis is typically made through a combination of clinical evaluation and imaging studies, including X-rays, which reveal the characteristic features of the deformity, such as the dorsal angulation of the distal radius and alignment of the ulnar styloid. Treatment options for Madelung deformity are tailored to the severity of the deformity and the associated symptoms. Conservative management may involve physical therapy aimed at improving wrist function and adapting to the limitations posed by the condition. However, in more severe cases, surgical intervention may be warranted. Surgical procedures can include osteotomy, where sections of bone are realigned, or wrist reconstruction surgeries that aim to restore more normal anatomy and improve wrist function. Post-operative rehabilitation is crucial for a successful outcome, allowing patients to regain strength and mobility in the wrist. Despite medical and surgical treatments, some individuals may continue to experience residual pain or limitations in wrist motion throughout their lives. Early recognition and management of Madelung deformity can significantly improve outcomes and quality of life for affected individuals, emphasizing the importance of awareness of this condition among both healthcare providers and families.